Products related to Chromosomes:
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Evolution, Composition and Regulation of Supernumerary B Chromosomes
Supernumerary B chromosomes (Bs) are dispensable genetic elements found in thousands of species of plants and animals, and some fungi. Since their discovery more than a century ago, they have been a source of puzzlement, as they only occur in some members of a population and are absent from others. When they do occur, they are often harmful, and in the absence of “selfishness”, based on mechanisms of mitotic and meiotic drive, there appears to be no obvious reason for their existence. Cytogeneticists have long wrestled with questions about the biological existence of these enigmatic elements, including their lack of any adaptive properties, apparent absence of functional genes, their origin, sequence organization, and co-evolution as nuclear parasites. Emerging new technologies are now enabling researchers to step up a gear, to look enthusiastically beyond the previous limits of the horizon, and to uncover the secrets of these “silent” chromosomes. This book provides a comprehensive guide to theoretical advancements in the field of B chromosome research in both animal and plant systems.
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Abnormal Chromosomes : The Past, Present, and Future of Cancer Cytogenetics
Explore the past, present, and future of cancer cytogeneticsIn Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics, globally renowned researchers Drs.Sverre Heim and Felix Mitelman deliver a state-of-the-art review of how cancer cytogenetic analyses have contributed to an improved understanding of tumorigenesis as well as to the diagnosis and treatment of cancer patients.The book also discusses how cytogenetics – the study of chromosomes - meets, interacts with, and cross-fertilizes other investigative technologies, including molecular somatic cell genetics. The book provides an impetus to think more deeply about the role chromosomes, and their abnormalities, play in health and disease, especially in neoplastic disorders.From which origins did cytogenetics develop? How did the finding of acquired chromosomal abnormalities in cells of leukemias and solid tumors influence our understanding of cancer as a biological process?How was information of this nature put to good use in the clinical management of cancer patients?Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics offers readers: A thorough introduction to ancient theories of disease, the advent of cellular pathology, and how a scientific interest in chromosomes developedComprehensive exploration of the conceptual importance of Theodor Boveri and his somatic mutation theory of cancerA detailed chronological resume of cancer cytogenetic discoveries during the 20th centuryIn-depth discussions of the role of chromosome abnormalities, oncogenes, and tumor suppressor genes in leukemias, lymphomas, and solid tumors, together with a survey of what chromosome analyses have revealed about the clonal evolution of neoplastic cell populationsA discussion of the importance of pathogenetic classifications of neoplastic diseases, the role chromosome abnormalities play in this context, and which technological breakthroughs can be expected in chromosome-oriented cancer research Abnormal Chromosomes: The Past, Present, and Future of Cancer Cytogenetics was written for everyone with a scientific or clinical interest in cancer, especially how acquired chromosome abnormalities lead to neoplastic transformation.The book teaches how cytogenetic analyses contribute to a better understanding of tumorigenesis, but also how the finding of specific chromosome aberrations can be crucial for the diagnosis, prognosis, and management of cancer patients.
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Critical Doubt
They met in a war-torn city on the other side of the world and shared an anonymous night of passion. They didn't intend to meet again. Nor did they think they'd be reunited by sinister secrets... Five years later, FBI Agent Savannah Kane is headed to a small town in Georgia for the funeral of her best friend's husband. Going home is fraught with complications, but Savannah never imagined one of those would be Ryker Stone, the stranger she'd shared an unforgettable night with.Haunted by an ambush that took the lives of two men in his unit, Ryker now copes by living a solitary civilian life. Attending the funeral of yet another soldier, this one lost to a senseless accident, he is shocked to run into the beautiful stranger he has never forgotten.When another man in Ryker's former unit dies under suspicious circumstances, it's clear that someone is targeting his team. He's determined to get the truth; Savannah is just as determined to get answers for her friend. Neither wants to work with the other, and as they struggle with trust and attraction, the truth grows murkier...and more dangerous. Will finding answers reveal secrets neither one of them is ready to know? Don't miss this twisting, suspenseful, romantic page-turner by #1 New York Times Bestselling Author Barbara Freethy!
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Questioning Qualitative Inquiry : Critical Essays
Is qualitative research in crisis? In Questioning Qualitative Inquiry Martyn Hammersley raises fundamental questions about the current state of qualitative social research.He examines some of the changes that have taken place within it over the past fifty years, suggesting that the move away from natural science as a model, and towards an appeal to literature and art, involves rejection of key principles that are essential to research of any kind. Hammersley argues that, in important respects, qualitative inquiry has not lived up to the claims originally made on its behalf, and that more recent developments have worsened the situation.Insufficient attention has been given to the problems surrounding leading ideas like thick description, analytic induction, and constructionism.The argument is pursued through discussion of the work of influential writers - such as Clifford, Geertz, Denzin and Lincoln - and by detailed examination of concrete issues, like the value of interview data, the rationales for discourse and conversation analysis, the role of rhetoric in research reports, and the nature of assessment criteria.At a time when qualitative inquiry is coming under renewed challenge in some quarters, the task of addressing the methodological problems it faces has become urgent. These essays on current developments and debates are essential reading for anyone interested in the future of qualitative research.
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What is your question about chromosomes?
My question about chromosomes is: How do abnormalities in chromosome structure or number lead to genetic disorders and diseases?
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Are a chromatid chromosome and two chromatid chromosomes homologous chromosomes or a set of chromosomes?
A chromatid chromosome and two chromatid chromosomes are not homologous chromosomes, but rather a set of chromosomes. Homologous chromosomes are pairs of chromosomes that contain the same genes in the same order, one from each parent. In contrast, chromatid chromosomes are duplicated copies of a single chromosome that are joined together at the centromere. Two chromatid chromosomes refer to a duplicated chromosome in preparation for cell division.
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Are chromosomes unreliable?
Chromosomes are not inherently unreliable, as they are the structures that carry our genetic information and play a crucial role in cell division and inheritance. However, errors can occur during the process of chromosome replication and segregation, leading to genetic mutations and disorders. Additionally, environmental factors and lifestyle choices can also impact the stability and integrity of chromosomes. Overall, while chromosomes are essential for the functioning of our cells and the inheritance of genetic traits, they are not immune to errors and can be influenced by various factors.
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What is the difference between single chromosomes and double chromosomes?
Single chromosomes refer to a single strand of DNA that contains genetic information. In contrast, double chromosomes refer to a pair of identical chromosomes, one from each parent, that are joined together at the centromere. Single chromosomes are found in haploid cells, such as gametes, while double chromosomes are found in diploid cells, such as somatic cells. Double chromosomes allow for genetic diversity and the exchange of genetic material through processes such as meiosis and fertilization.
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Pragmatic Inquiry : Critical Concepts for Social Sciences
This book examines a range of critical concepts that are central to a shift in the social sciences toward "pragmatic inquiry," reflecting a twenty-first century concern with particular problems and themes rather than grand theory. Taking a transnational and transdisciplinary approach, the collection demonstrates a shared commitment to using analytical concepts for empirical exploration and a general orientation to research that favors an attention to objects, techniques, and practices.The chapters draw from broad-based and far-reaching social theory in order to analyze new, specific challenges, from grasping the everyday workings of markets, courtrooms, and clinics, to inscribing the transformations of practice within research disciplines themselves.Each contributor takes a key concept and then explores its genealogies and its circulations across scholarly communities, as well as its proven payoffs for the social sciences and, often, critical reflections on its present and future uses.This carefully crafted volume will significantly expand and improve the analytical repertoires or toolkits available to social scientists, including scholars in sociology or anthropology and those working in science and technology studies, public health, and related fields.
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Scientific Methods of Inquiry for Intelligence Analysis
Since 9/11, the needs of intelligence agencies as well as the missions they conduct have increased in number, size, and complexity.As such, government and private security agencies are recruiting staff to analyze the vast amount of data collected in these missions.This textbook offers a way of gaining the analytic skills essential to undertake intelligence work.It acquaints students and analysts with how intelligence fits into the larger research framework.It covers not only the essentials of applied research, but also the function, structure, and operational methods specifically involved in intelligence work.It looks at how analysts work with classified information in a security conscious environment as well as obtain data via covert methods.Students are left with little doubt about what intelligence is and how it is developed using scientific methods of inquiry. This revised edition of the popular text has been expanded and updated significantly.
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Critical Discourse Analysis : The Critical Study of Language
Bringing together papers written by Norman Fairclough over a 25 year period, Critical Discourse Analysis represents a comprehensive and important contribution to the development of this popular field. The book is divided into seven sections covering the following themes: language in relation to ideology and powerdiscourse in processes of social and cultural change dialectics of discourse, dialectical relations between discourse and other moments of social lifemethodology of critical discourse analysis research analysis of political discourse discourse in globalisation and 'transition' critical language awareness in education The new edition has been extensively revised and enlarged to include a total of twenty two papers.It will be of value to researchers in the subject and should prove essential reading for advanced undergraduate and postgraduate students in Linguistics and other areas of social science.
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Cancel Culture : A Critical Analysis
“Cancel culture” has become one of the most charged concepts in contemporary culture and politics, but mainstream critiques from both the left and the right provide only snapshots of responses to the phenomenon.Takinga media and cultural studies perspective, this book traces the origins of cancel practices and discourses, and discusses their subsequent evolution within celebrity and fan cultures, consumer culture, and national politics in the U.S. and China. Moving beyond popular press accounts about the latest targets of cancelling or familiar free speech debates, this analysis identifies multiple lineages for both cancelling and criticisms about cancelling, underscoring the various configurations of power associated with “cancel culture” in particular cultural and political contexts.
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What is the difference between chromosomes, chromatids, and double chromosomes?
Chromosomes are the structures within cells that contain genetic information. They are made up of DNA and proteins. Chromatids are the two identical copies of a chromosome that are formed during the process of DNA replication. Double chromosomes, on the other hand, refer to the paired chromosomes that are formed during cell division, with each chromosome consisting of two sister chromatids. In summary, chromosomes are the overall structures containing genetic material, chromatids are the individual copies of a chromosome, and double chromosomes are the paired chromosomes formed during cell division.
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Does a homologous pair of chromosomes consist of two single-chromatid chromosomes or two double-chromatid chromosomes?
A homologous pair of chromosomes consists of two single-chromatid chromosomes. Each chromosome in the pair comes from one parent, and they carry the same genes in the same order, but may have different versions of those genes. During the S phase of the cell cycle, each single-chromatid chromosome replicates to form a double-chromatid chromosome, but these double-chromatid chromosomes do not pair up with each other during normal cell division.
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What is the difference between chromatids, chromosomes, and pairs of chromosomes?
Chromatids are two identical copies of a chromosome that are joined together at the centromere. Chromosomes are thread-like structures made of DNA and proteins that contain genetic information. Pairs of chromosomes refer to two homologous chromosomes, one inherited from each parent, that carry similar genes but may have different variations. In summary, chromatids are the duplicated copies of a single chromosome, chromosomes are the structures that contain genetic material, and pairs of chromosomes are homologous chromosomes inherited from each parent.
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What is the difference between double chromosomes and homologous double chromosomes?
Double chromosomes refer to a pair of identical chromosomes that are present in a diploid organism, one inherited from each parent. On the other hand, homologous double chromosomes are a pair of chromosomes that are similar in size, shape, and genetic content, but not identical. Homologous chromosomes carry the same genes in the same order, but may have different versions of those genes (alleles) due to genetic variation.
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